Synergistic Convergence in Congenital Extraocular Muscle Misinnervation

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Synergistic convergence in congenital extraocular muscle misinnervation.

S ynergistic divergence is a well-established clinical condition in which abduction arises on attempted adduction, leading to simultaneous abduction of both eyes on lateral gaze. Synergistic divergence can occur as an extreme form of Duane syndrome, where most if not all oculomotor nerve branch fibers originally directed to the medial rectus muscle innervate the lateral rectus muscle. Synergist...

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Although on cover test the child maintained fixation easily with either eye, he preferred to view with the right eye. A marked left convergent strabismus was present, the deviation being greater on accommodation; the cover test also showed alternating hypertropia. When fixing with the right eye the horizontal deviation was approximately 35A with left hypertropia and when fixing with the left ey...

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Motor nucleus activity fails to predict extraocular muscle forces in ocular convergence.

For a given eye position, firing rates of abducens neurons (ABNs) generally (Mays et al. 1984), and lateral rectus (LR) motoneurons (MNs) in particular (Gamlin et al. 1989a), are higher in converged gaze than when convergence is relaxed, whereas LR and medial rectus (MR) muscle forces are slightly lower (Miller et al. 2002). Here, we confirm this finding for ABNs, report a similarly paradoxical...

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Oculomotor nerve and muscle abnormalities in congenital fibrosis of the extraocular muscles.

Congenital fibrosis of the extraocular muscles is an autosomal dominant congenital disorder characterized by bilateral ptosis, restrictive external ophthalmoplegia with the eyes partially or completely fixed in an infraducted (downward) and strabismic position, and markedly limited and aberrant residual eye movements. It has been generally thought that these clinical abnormalities result from m...

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INTRODUCTION Extraocular muscle tenotomy has been reported to damp congenital nystagmus in an achiasmatic sheepdog. We performed extraocular muscle tenotomy to evaluate its effects on congenital nystagmus in primates. METHODS Magnetic search coil eye movement recordings were used to document the presence of horizontal congenital nystagmus in 2 adult macaque monkeys that also had naturally occ...

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ژورنال

عنوان ژورنال: Archives of Ophthalmology

سال: 2008

ISSN: 0003-9950

DOI: 10.1001/archopht.126.4.574